Fig. 3.

Kaplan–Meier Plot of Overall Survival Abbreviations: Inf.U = infectious units; PD-1/L1 = programmed death 1/programmed death ligand 1; RECIST = Response Evaluation Criteria In Solid Tumors. Legend: Cohort 1 = First-line treatment, ineligible for cisplatin-containing chemotherapy. Cohort 2 = Second-line treatment, previously treated with standard first-line cisplatin-based chemotherapy, PD-1/L1 inhibitor naïve. The figure includes all subjects who received any amount of trial vaccine, whether MVA-BN-CV301 alone or followed by FPV-CV301. Kaplan–Meier method estimates were used to create the figure. Overall survival included death due to any cause. Subjects were censored at the end of the follow-up, early termination, or the last attended trial visit if subjects were ongoing with no survival endpoint