Table 1.

NCI-CTCAE v. 5.0 grading of pericardial disease

CTCAE term	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Pericardial effusion	–	Asymptomatic effusion size small to moderate	Effusion with physiologic consequences	Life-threatening consequences; urgent intervention indicated	Death
Pericardial tamponade	–	–	–	Life-threatening consequences; urgent intervention indicated	Death
Pericarditis	Asymptomatic, ECG or physical findings (e.g., rub) consistent with pericarditis	Symptomatic pericarditis (e.g., chest pain)	Pericarditis with physiologic consequences (e.g., pericardial constriction)	Life-threatening consequences; urgent intervention indicated	Death