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Metabolic genes involved in LUAD meta-cohorts. a Unsupervised clustering of metabolic genes for 2181 patients in meta-cohorts. b t-distributed stochastic neighbor embedding (t-SNE) analysis based on metabolic genes clearly separated tumor and normal tissue. c Kaplan–Meier curves showing the association between Metclusters and OS of 2181 patients in meta-cohorts (log-rank test, P < 0.001)
