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. 2022 Apr 4;9(1):39. doi: 10.1186/s40643-022-00526-2

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Fractionation of Pepsin-ISPH by molecular weight cut-off (MWCO) membrane. A fraction chart. B effect of 4000 ppm Pepsin-ISPH and its retentates/permeate on relative phagocytosis (%) in mouse macrophage RAW246.7 cells. Dosage effect of Pepsin-ISPH and its retentates/permeate, 2000 ppm (C) and 4000 ppm (D) on NO concentration in mouse macrophage RAW246.7 cells. LPS (1 ppm) was used as positive control. Bars represent mean ± standard deviation (SD; n = 3). Mean with different letters are significantly different (p < 0.05) by Duncan’s multiple range test