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. 2021 Mar 26;70(11):3113–3122. doi: 10.1007/s00262-021-02906-7

Fig. 2.

Fig. 2

Relationship between expression of V-domain Ig suppressor of T cell activation (VISTA) in ICs and clinicopathologic features. The higher VISTA expression in ICs was correlated with higher tumor stage (Spearman’s rank correlation = 0.325, p < 0.001), higher pathologic grade (Spearman’s rank correlation = 0.438, p < 0.001), tumor size larger than 3 cm (Spearman’s rank correlation = 0.322, p < 0.001), and multiple cancer lesions (Spearman’s rank correlation = 0.203, p = 0.01)