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. 2022 Aug 4;72(2):427–435. doi: 10.1007/s00262-022-03265-7

Table 2.

Patient characteristics in the CAR group

Characteristic CAR
 < 0.62  ≥ 0.62
n = 68 n = 25 p Value
(%) (%)
Age (years) 69.0 [38–83] 70 [42–85] 0.57
Median [range]
Sex 53/15 19/6 1.00
Male/Female (78/22) (76/24)
Primary 5/62/1 1/24/0 0.69
Cervical/Thoracic/EGJ (7/91/2) (4/96/0)
No. of metastatic sites 51/17 16/9 0.31
1/ ≥ 2 (75/25) (64/36)
Lung metastasis 43/25 15/10 0.81
No/Yes (63/37) (60/40)
Liver metastasis 48/20 18/7 1.00
No/Yes (70/30) (72/28)
Peritoneal metastasis 66/2 23/2 0.29
No/Yes (97/3) (92/8)
Previous Surgery 39/29 17/8 0.47
No/Yes (57/43) (68/32)
Previous Radiotherapy 40/28 11/14 0.24
No/Yes (59/41) (44/56)
No. of previous regimens 42/26 17/8 0.64
1/ ≥ 2 (62/38) (68/32)
Received treatment after nivolumab 31/37 16/9 0.16
No/Yes (46/54) (64/36)
BMI 29/39 16/9 0.10
 < 18.5/ ≥ 18.5 (43/57) (64/36)
ECOG PS 34/34 8/17 0.16
0/ ≥ 1 (50/50) (32/68)
Disease control 44/24 18/7 0.62
No/Yes (65/35) (72/28)
Objective response 55/13 20/5 1.00
No/Yes (80/20) (80/20)
irAE 44/24 18/7 0.62
No/Yes (65/35) (72/28)

p Value: Fisher’s exact test and the value of the comparison between the CAR group and the other groups. CAR, C-reactive protein/albumin ratio