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In the design of CAR-M, Prof Rong Xiang and Yi Shi from Nankai University have given good suggestions. Sincere acknowledgment to them for their kindly support. Elements used for Fig.2b in this article were downloaded from https://smart.servier.com. The Servier Medical Art by Servier is licensed under a Creative Commons Attribution 3.0 Unported License. This work was supported by the Prospective Research Program of the Foundation for the Development of Frontier Technology of Cell Therapy of Changzhou Xitaihu (2022-P-009, Y.L.), the Fundamental Research Funds for the Central Universities (3332022181, Z.D.) and the Bilateral Inter-Governmental S&T Cooperation Project from Ministry of Science and Technology of China (2018YFE0114300, Y.L.).