Table 2.

Bivariate analysis of baseline individual medical comorbidities and the modified Charlson comorbidity index score with overall survival

		Frequency, n (%) (n = 671)	Median OS [95% CI] (months)	p value
Congestive heart failure	Absent	623 (92.8)	13.9 [11.5, 16.2]	< 0.01
	Present	48 (7.2)	8.1 [4.5, 17.2]
Pulmonary disease	Absent	510 (76.0)	13.8 [11.2, 16.2]	0.19
	Present	161 (24.0)	12.1 [9.1, 17.3]
Diabetes without complications	Absent	537 (80.0)	13.8 [11.0, 16.7]	0.54
	Present	134 (20.0)	12.1 [9.3, 15.7]
Diabetes with complications	Absent	649 (96.7)	13.2 [10.8, 15.8]	0.93
	Present	22 (3.3)	14.5 [9.3, 29.3]
Hemiparaplegia	Absent	660 (98.3)	13.8 [11.3, 16.0]	0.08
	Present	11 (1.6)	8.1 [1.5, 22.5]
HIV	Absent	669 (99.7)	13.5 [11.2, 15.8]	0.724
	Present	2 (0.03)	NR
Liver disease (mild)	Absent	607 (90.5)	13.9 [11.4, 16.2]	0.16
	Present	64 (9.5)	10.5 [5.8, 16.2]
Liver disease (moderate or severe)	Absent	668 (99.6)	13.6 [11.3, 16.0]	< 0.01
	Present	3 (0.04)	1.0 [0.6, 0.8]
Myocardial infarction	Absent	550 (82.0)	14.2 [11.4, 17.1]	< 0.01
	Present	121 (18.0)	10.1 [7.9, 14.5]
Peptic ulcer disease	Absent	644 (96.0)	13.6 [11.3, 15.8]	0.56
	Present	27 (4.0)	10.1 [7.9, 14.5]
Peripheral vascular disease	Absent	619 (92.3)	13.1 [10.8, 15.7]	0.98
	Present	52 (7.7)	16.2 [8.6, 23.9]
Renal disease	Absent	616 (91.8)	13.2 [10.8, 15.7]	0.83
	Present	55 (8.2)	16.2 [8.2, 18.3]
Cerebrovascular disease	Absent	601 (89.6)	13.8 [11.5, 16.2]	0.06
	Present	70 (10.4)	9.3 [6.9, 16.0]
Dementia	Absent	668 (99.6)	13.5 [11.3, 15.8]	0.96
	Present	3 (0.04)	6.2 [4.7, NR]
Connective tissue disorder	Absent	661 (98.5)	13.8 [11.3, 16.2]	< 0.01
	Present	10 (1.5)	3.4 [1.0, 10.0]
mCCI score	0	255 (38.0)	17.0 [13.2, 21.3]	< 0.01
	1	189 (28.2)	13.1 [9.9, 17.4]
	≥ 2	227 (33.8)	10 [8.2, 13.2]

OS overall survival, mCCI modified Charlson comorbidity index