Fig. 5.

Effects of TGF-β2 inhibition by TASO on recruitment of human T cells in spleen. Subpopulation of Tregs is regulated by TGF-β2 inhibition in spleen. a Recruitment of human T cells in spleen was measured by IHC staining against human Foxp3 and human CD8. The human Foxp3 positive cells b and human CD8 + cells c were counted, and the density of cells (no. of 0.1 mm²) for phenotype of Tregs and cytotoxic T cells was determined, respectively. The results are expressed as mean ± S.E.M. obtained from five mice. **p < 0.01 vs. PBMC + vehicle (Dunnett’s test). Bar = 100 μm