The relationships between mutation profile and TMB in high- and low-risk groups. A Mutation profile of THCA patients in high- and low-risk groups. B The difference of TMB in high- and low-risk groups. C The association of TMB and OS and PFI of THCA patients. D The association between IPS and the immune-related prognostic signature. E The expression of PD-1, PD-L1, PD-L2, CTLA4, TIGIT, and TIM-3 in high- and low-risk groups