TABLE 2.

Neutralization of HIV-1 strain MN and four NR variant viruses obtained from it by human sera and lack of correlation between susceptibility to V3 peptide blocking of strain MN neutralization

Human seruma	Reciprocal of NA titer against virus variant:					Fold inhibition of MN NA by V3 peptideb
	MN	C2	E4	E11	F3
NY-2	12,800	256	128	128	256	1
NY-3	25,600	32	8	16	16	128
NY-5	12,800	64	32	64	64	16
NY-7	6,400	32	16	NTc	NT	4
NY-9	51,200	1,024	256	512	256	32
L-1	12,800	64	32	32	64	NT
L-2	512	16	NT	NT	NT	1
L-3	1,024	16	16	NT	NT	4

^aSera were obtained from the NYBC (NY designations) and from patients who participated in studies of AIDS pathogenesis at the NIH (L designations). 

^bFold inhibition was determined at a peptide concentration of 100 μg/ml for NY-7, L-2, and L-3 and at 10 μg/ml for the rest of the sera. 

^cNT, not tested.