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. 2024 Mar 20;13:e54342. doi: 10.2196/54342

Table 1.

Study measures.

Measure Items Baseline Weekly 3 months 6 and 9 months
Baseline measures

Demographic information, MOUDa information, and clinical characteristics of chronic pain




MINIb International Neuropsychological Interview [59] Interview



Graded Chronic Pain Scale–Revised (frequency, severity, and impact of pain) [53] 6



Addiction Severity Index [60] Interview
Primary outcome (in 3 months)

Buprenorphine retention none
Secondary outcome measures

PROMISc Pain Interference 6a [61] 6

MOUD Adherenced None

The Craving Scale [62] 3

Timeline Follow-Back Substance Use Calendar [63] Interview

Urine toxicology None

NRSe Pain Intensity Rating [64] 1

PROMIS Physical Function 6b [65] 7

Pain Catastrophizing Scale [66] 14

Pain Self-Efficacy Questionnaire [67] 11

PROMIS Sleep Disturbance 6a and Duration [68] 9
Other measures

Brief Symptom Inventory [69] 18

Cold pressor task None

PHQ-4f (brief screen for anxiety and depression) [70] 4

Program and Client Cost-Substance Abuse Treatment (treatment use) [71] Interview

IMPACTg engagement data (IMPACT+TAUh only) None


aMOUD: medications for opioid use disorder.

bMINI: Mini-International Neuropsychiatric Interview.

cPROMIS: Patient Reported Outcomes Measurement Information System.

dAdherence will be assessed with the Timeline Followback for daily MOUD use for the previous week, clinic dispensing records, and urine toxicology screen for buprenorphine or methadone collected at each weekly assessment visit.

eNRS: Numerical Rating Scale.

fPHQ-4: Patient Health Questionnaire-4.

gIMPACT: Integrating the Management of Pain and Addiction via Collaborative Treatment.

hTAU: treatment as usual.