REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial strains
USA300 FPR3757 JE2 (referred to as USA300)	BEI Resources Nebraska Library	https://doi.org/10.1128/mBio.00537-12
Transposon insertions in USA300 FPR3757
SAUSA300_0658 (ccpE)
position 898566 between SAUSA300_0818 (sufC) and SAUSA300_0819 (sufD)
SAUSA300_1232 (katA)
SAUSA300_1542 (hrcA)
SAUSA300_1708 (rot)
SAUSA300_1797 (xdrA)
SAUSA300_1842 (perR)
SAUSA300_2037 (cshA)
Biological samples
Newborn calf serum	Sigma	12023C-500ML
Sheep blood (5%) agar plates	Bio-Mérieux	43041
Powdered skim milk	Regilait	Supermarket
Chemicals, peptides, and recombinant proteins
Fatty acids C14, C16	Sigma	CAS # and product #: 544-63-8 & M3128; 57-10-3 & P0500
Fatty acid C18:1cis	Larodan, Sweden	CAS # & product #: 112-80-1 & 10-1801
Triclosan (Irgasan)	Sigma	CAS # & product #: 3380-34-5 & 72779
AFN-1252	MedChem Express	CAS # & product #: 620175-39-5 & HY-16911
Hydrogen peroxide (H2O2)	Sigma	CAS # & product #: 7722-84-1 & H1009
Phenazine-methosulfate (PMS)	Sigma	CAS # & product # 299-11-6 & P9625
Rhodamine B (for lipase detection)	Sigma	CAS # 81-88-9
Deposited data
Nanopore DNA genome sequence	Mendeley	https://doi.org/10.17632/grt4htck9k.1
Proteomics (14 conditions in quadruplicate)	Pride partner repository	http://proteomecentral.proteome.xchange.org Identifier PPXD034256
Phosphoproteomics data	Center for Computational Mass Spectrometry 395 repository University of California, San Diego	http://massive.ucsd.edu/ProteoSAFe/status.jsp?task=db3f5002e32e4a47a71996358bc6ae8c Identifier MassIVE MSV000089781
Experimental models: Cell lines
THP-1 differentiated macrophages	Institut Cochin collection	https://doi.org/10.1101/2022.12.02.518834
Experimental models: Organisms/strains
Galleria mellonella	Micalis institute Facilities
Oligonucleotides
Primer 5'-3'	Oligo name	Locus
GCAGGCACATATTGGTGAAGT	ccpE_F	SA300_0658
GATCCACTGTAATAGTTGCATGG	ccpE_R
GAAGAAGGATATGAATGGGT	sufD∗_F	position 898566 between SAUSA300_0818 and SAUSA300_0819
GGCTTTAGAATAATCAACAAG	sufD∗_R
GAACGCAACAAGGTATTGAA	katA_F	SAUSA300_1232
CCTCAGTCATTACTTGAATAT	katA_R
GAGCGACATAACTTGAATGTTAG	hrcA_F	SAUSA300_1542
GCATAGCTGTAGGTCCAATCA	hrcA_R
GCATTGCTGTTGCTCTACTTGC	rot_F	SAUSA300_1708
CGACACTGTATTTGGAATTTTGCA	rot_R
GGTTCGTATAGAGGCTGGTTA	xdrA_F	SAUSA300_1797
GTACCGAAAATTGGTTGGTTATCT	xdrA_R
CCAATATCTTTAAACACTCT	perR_F	SAUSA300_1842
CATCATTGCGACAAGCAGGC	perR_R
GGTCTGCTTCCACCGCTGC	cshA_F	SAUSA300_2037
ACTTTTACAAGAGTTAGTAGAAGC	cshA_R
Software and algorithms
D-Genies	Dot plot large Genomes	https://dgenies.toulouse.inra.fr/
GraphPad Prism 9.5.1	GraphPad Software Kaplan-Meier Log rank Mantel-Cox Cox proportional hazard Non-parametric Mann-Whitney	https://www.graphpad.com/
Rstudio	K-means clustering analysis	https://www.rstudio.com/products/rstudio/download/#download
X!TandemPipeline C++, MassChroQ, MCQR	Free resource proteomics analyses	https://forgemia.inrae.fr/pappso
Other
DNeasy® Blood & Tissue Kit	Qiagen	Cat No./ID: 69504
HaltTM Protease & Phosphatase Inhibitor Cocktail (100X)	Thermo Scientific, Fr	Référence: 78430
Nuclease detection medium	DNase agar (Oxoid, Thermo Scientific, Fr)	CM0321