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. 2024 Apr 3;81(6):631–632. doi: 10.1001/jamapsychiatry.2024.0299

Table. Model-Fitting Results and Parameter Estimates of Obsessive-Compulsive Disorder Liability Heritability, Adjusted for Sex and Birth Yeara.

Model Model-fitting results Parameter estimates, % (95% CI)
−2 Log-likelihood statistic df Δχ2df)b P value Akaike information criterion Model compared with A C E
1. Saturated 8678.428 132 385 NA NA 8696.428 NA NA NA NA
2. ACE 8679.764 132 388 1.336 (3) .72 8693.764 1 59.9 (24.4 to 95.8) −8.6 (−39.2 to 20.0) 48.7 (38.1 to 60.8)
3. AEc 8680.094 132 389 0.330 (1) .56 8692.094 2 50 (38.8 to 60.1) NA 50 (40.0 to 61.3)
4. CE 8690.732 132 389 10.968 (1) <.001 8702.732 2 NA 35.9 (26.9 to 44.3) 64.1 (55.7 to 73.1)
5. E 8743.899 132 390 64.135 (2) <.001 8753.899 2 NA NA 100 (100 to 100)

Abbreviations: A, additive genetic; C, shared environmental; E, nonshared environmental; NA, not applicable.

a

Variance components are not constrained to be positive in the presented models.

b

The difference in −2 log-likelihood statistic and df between the submodel and the full model.

c

AE was the best-fitting model.