Figure 1.

MRI adipocytic differentiation in pleomorphic liposarcoma during anthracycline-based chemotherapy. A 56-year-old female presented with a 14cm-long Grade III pleomorphic liposarcoma of the left lumbar muscles. On baseline MRI, the tumor displayed areas with fatty signal, i.e. areas with high SI on Fat image of Dixon gradient echo T ₁ weighted imaging (‘Ax Dixon Fat T1’) and sagittal turbo spin echo T ₁ weighted imaging (‘Sag T1’). During chemotherapy, MRI performed after 2 and 6 cycles (‘Post-C2’ and ‘Post-C6’. respectively) showed an increase in the amount of fatty areas (white arrows), especially at the lower and anterior sides of the tumor—without noticeable change in longest diameter (+0.5%). SI, signal intensity.