FIGURE 1.

SHP2 was overexpressed in gastric cancer tissues, and indicated a poor prognosis. (A) The expression level of PTPN11, a gene encoding SHP2, in different tumors. (B) The expression level of SHP2 in gastric cancer tissues. (C) SHP2 expression in GC and normal tissues adjacent to the tumor (NAT) was detected by immunohistochemistry. scale bar = 500 µm. (D) The immunoreactive score of (C) (n = 12 pairs). (E) The correlation between SHP2 expression and overall survival in GC was counted with the log‐rank test. *p < 0.05; **p < 0.01; and ***p < 0.001.