Table 1. Optimization of the Wittig Reaction for 7^a.

entry	6 (equiv)	R	solvent	temp. (°C)	time (h)	yield (%)b
1	6a (1.0)	H	DCM	25	12	35
2	6a (1.5)	H	DCM	25	12	42
3	6a (1.5)	H	DCM	0	24	65
4	6a (1.5)	H	DCM	–20	48	0
5	6a (1.5)	H	Et2O	0	24	62
6	6a (1.5)	H	THF	0	24	58
7	6a (1.5)	H	DMF	0	24	47
8	6b (1.5)	4-F	DCM	0	24	62
9	6c (1.5)	3-F	DCM	0	24	71
10	6d (1.5)	4-Cl	DCM	0	24	52
11	6e (1.5)	4-Br	DCM	0	24	58
12	6f (1.5)	4-CH3O	DCM	0	24	84
13	6g (1.5)	3-CH3O	DCM	0	24	72
14	6h (1.5)	4-CH3	DCM	0	24	57

^aReactions were performed with 1.0 or 1.5 equiv of Wittig reagents 6 under the given conditions.

^bIsolated yields.