Summary of reactive case detection and treatment (RACDT) and reactive drug administration (RDA) outcomes and Grading of Recommendations, Assessment, Development, and Evaluations for each. RCT = randomized controlled trial; NRS = nonrandomized study. 1Rated not serious on risk of bias, inconsistency, indirectness; rated serious on imprecision. 2Rated not serious on risk of bias, inconsistency; rated serious on indirectness, imprecision. 3Rated not serious on risk of bias, inconsistency, imprecision; rated serious on indirectness. 4Rated serious on risk of bias; rated not serious on inconsistency, indirectness, imprecision. 5Rated not serious on risk of bias, inconsistency; rated very serious on indirectness; rated serious on imprecision. 6Rated not serious on risk of bias, inconsistency; rated very serious on indirectness; rated serious on imprecision.