Table 2:
Top: Univariate analysis of overall survival. Bottom: Combined Univariate and Multivariate analysis of overall survival. 95% confidence intervals and hazard ratios shown. Significance calculated as p<0.005, highlighted in bold. Comparison groups in bold. Abbreviations: HR: hazard ratio.
| Univariate analysis | N | HR (95% CI) | P Value | ||||
|---|---|---|---|---|---|---|---|
| Grade category | Moderately differentiated | 1163 | 1.14 (0.97–1.33) | 0.11 | |||
| Poorly/Undiffer entiated | 1543 | 1.56 (1.33–1.81) | <.001 | ||||
| Well differentiated | 209 | - | - | ||||
| Chemotherap y at any CoC Facility | Single-agent chemotherapy | 587 | 0.54 (0.49–0.60) | <.001 | |||
| Multiagent chemotherapy | 1335 | 0.46 (0.42–0.50) | <.001 | ||||
| None | 1278 | - | - | ||||
| Univariate analysis | Category | Univar iate N | Univariate HR (95% CI) | Univariate P value | Multivariate N | Multivariate HR (95% CI) | Multivariate P value |
| Facility Type | Community Cancer Program | 387 | 1.57 (1.39–1.76) | <.001 | 382 | 1.39 (1.23–1.56) | <.001 |
| Comprehensive Community Cancer Program | 1628 | 1.41 (1.31–1.52) | <.001 | 1614 | 1.34 (1.24–1.44) | <.001 | |
| Integrated Network Cancer Program | 545 | 1.32 (1.19–1.46) | <.001 | 540 | 1.30 (1.17–1.45) | <.001 | |
| Academic/Rese arch Program | 1525 | - | - | 1469 | - | - | |
| Facility region | South | 1408 | 1.16 (1.06–1.27) | <.001 | 1376 | 1.11 (1.01–1.21) | 0.029 |
| Midwest | 1120 | 1.21 (1.10–1.32) | <.001 | 1087 | 1.16 (1.05–1.27) | 0.003 | |
| West | 701 | 1.08 (0.97–1.20) | 0.14 | 637 | 1.11 (1.00–1.24) | 0.059 | |
| Northeast | 916 | - | - | 905 | - | - | |
| Sex | Female | 2932 | 0.93 (0.87–1.00) | 0.046 | 2834 | 0.92 (0.85–0.98) | 0.016 |
| Male | 1213 | - | - | 1171 | - | - | |
| Race category | Black | 575 | 0.94 (0.86–1.03) | 0.205 | 554 | 1.02 (0.93–1.13) | 0.638 |
| Asian/Other | 281 | 0.82 (0.72–0.93) | 0.002 | 262 | 0.91 (0.80–1.05) | 0.193 | |
| White | 3289 | - | - | 3189 | - | - | |
| Age category (median) | Greater than 69 y.o. | 1984 | 1.51 (1.42–1.61) | <.001 | 1952 | 1.19 (1.10–1.28) | <.001 |
| Less than or equal to 69 y.o. | 2161 | - | - | 2053 | - | - | |
| Charlson-Deyo Score | 1 | 918 | 1.20 (1.11–1.30) | <.001 | 910 | 1.15 (1.07–1.25) | <.001 |
| 2+ | 322 | 1.67 (1.48–1.88) | <.001 | 318 | 1.44 (1.27–1.62) | <.001 | |
| 0 | 2905 | - | - | 2777 | - | - |