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. 2023 Nov 7;44(2):239–251. doi: 10.1177/0271678X231212378

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Figure 6. — FosDT levels are regulated by NF-κB. When treated with NF-κB inhibitor BAY 11-7082 (IP) at 30 min of reperfusion following transient MCAO, FosDT^+/+ rats showed significantly reduced levels of FosDT (a) and Fos mRNA (b) at 12 h of reperfusion compared with vehicle control. FosDT^−/− rats showed no FosDT expression (a) and no change in Fos levels (b) by BAY 11-7082 treatment. Values are mean ± SD (n = 4/group). *p < 0.05 compared with FosDT^+/+ sham group and ^#p < 0.05 compared with FosDT^+/+ MCAO group treated with the vehicle by one-way ANOVA followed by Sidak’s multiple comparisons post-test.