Table 2.

Diagnostic performance of the quantitative-semantic model, radiomic models, and frozen section model for differentiating invasive adenocarcinomas from adenocarcinoma in situ/minimally invasive adenocarcinomas in the primary and validation cohorts

	AUC	Sensitivity	Specificity	Accuracy
Primary cohort
Quantitative-semantic model	0.879 (0.801-0.935)	0.767 (0.614-0.882)	0.900 (0.795-0.960)	0.845 (0.760-0.909)
Radiomic model of low-dose CT	0.929 (0.862-0.971)	0.907 (0.779-0.974)	0.867 (0.754-0.941)	0.883 (0.805-0.938)
Radiomic model of standard-dose CT	0.941 (0.876-0.978)	0.814 (0.666-0.916)	0.950 (0.861-0.990)	0.893 (0.817-0.945)
FS model	0.884 (0.805-0.938)	0.884 (0.749-0.961)	0.883 (0.774-0.952)	0.883 (0.805-0.938)
Validation cohort
Quantitative-semantic model	0.897 (0.768-0.968)	0.737 (0.488-0.909)	0.920 (0.740-0.990)	0.841 (0.699-0.934)
Radiomic model of low-dose CT	0.933 (0.815-0.986)	0.842 (0.604-0.966)	0.800 (0.593-0.932)	0.818 (0.673-0.918)
Radiomic model of standard-dose CT	0.901 (0.773-0.970)	0.789 (0.544-0.939)	0.840 (0.639-0.955)	0.818 (0.673-0.918)
FS model	0.828 (0.685-0.925)	0.737 (0.488-0.909)	0.920 (0.740-0.990)	0.841 (0.699-0.934)

AUC, area under curve; FS, frozen section. Numbers in the parentheses are 95% confidence interval