Table 1:
Baseline Characteristics of the Patient Cohort
| AF Patients with Sarcoidosis |
AF Patients Without Sarcoidosis |
P Value | |||
|---|---|---|---|---|---|
| n | % | n | % | ||
| No. of admissions | 1031 | 0.3 | 387,380 | 99.7 | |
| Baseline characteristics | |||||
| Age, mean (SD), years | 67.70 (11.43) | 71.63 (12.45) | <.01 | ||
| Female sex | 630 | 61.1 | 200,145 | 51.7 | <.01 |
| Anemia | 45 | 4.4 | 16,178 | 4.2 | .76 |
| Catheter ablation for AF | 50 | 4.9 | 14,429 | 3.7 | .06 |
| CHA2DS2-VASc score, points | 3 (2) | 3 (2) | .14 | ||
| Chronic kidney diseases | 266 | 25.8 | 76,206 | 19.7 | <.01 |
| Chronic liver disease | 45 | 4.4 | 12,604 | 3.3 | .05 |
| Chronic pulmonary disease | 376 | 36.5 | 94,541 | 24.4 | <.01 |
| Coagulation disorder | 58 | 5.6 | 18,700 | 4.8 | .23 |
| Coronary artery disease | 293 | 28.4 | 127,991 | 33.0 | <.01 |
| Heart failure | 205 | 19.9 | 55,560 | 14.3 | <.01 |
| Hyperlipidemia | 547 | 53.1 | 213,010 | 55.0 | .21 |
| Hypertension | 841 | 81.6 | 314,372 | 81.2 | .73 |
| Malignancy | 52 | 5.0 | 19,769 | 5.1 | .93 |
| Non-ischemic cardiomyopathy | 320 | 31.0 | 86,911 | 22.4 | <.01 |
| Obstructive sleep apnea | 266 | 25.8 | 70,398 | 18.2 | <.01 |
| Peripheral vascular disease | 131 | 12.7 | 39,930 | 10.3 | .01 |
| Prior myocardial infarction | 77 | 7.5 | 34,050 | 8.8 | .13 |
| Prior coronary artery bypass graft | 40 | 3.9 | 26,778 | 6.9 | <.01 |
| Prior ICD | 68 | 6.6 | 11,625 | 3.0 | <.01 |
| Prior PPM | 65 | 6.3 | 26,288 | 6.8 | .54 |
| Prior percutaneous coronary intervention | 88 | 8.5 | 41,436 | 10.7 | .03 |
| Prior stroke/transient ischemic attack | 100 | 9.7 | 49,395 | 12.8 | <.01 |
| Pulmonary hypertension | 172 | 16.7 | 33,450 | 8.6 | <.01 |
| Valvular heart disease | 203 | 19.7 | 82,869 | 21.4 | .18 |
| Charlson Comorbidity Index (%), points | <.01 | ||||
| 0 | 149 | 14.4 | 90,095 | 23.3 | |
| 1 | 236 | 22.9 | 98,240 | 25.3 | |
| ≥2 | 646 | 62.7 | 199,045 | 51.4 | |
| Elixhauser Comorbidity Score, points | <.01 | ||||
| <4 | 248 | 24.1 | 129,181 | 33.3 | |
| ≥4 | 783 | 75.9 | 258,199 | 66.7 | |
Abbreviations: AF, atrial fibrillation; ICD, implantable cardioverter-defibrillator; PPM, permanent pacemaker; SD, standard deviation.