Table 2.

Documented reasons for modification of treatment regimen among people with HIV during the follow-up.

Reason for modification	Total	Younger	Middle-aged	Older
Adverse drug reaction	7.38 (6.84–7.96)	7.73 (6.85–8.72)	6.09 (5.40–6.86)	11.93 (9.99–14.19)
Personal reasons	0.77 (0.60–0.98)	2.80 (1.89–4.11)	0.46 (0.29–0.73)	0.56 (0.34–0.90)
Polypharmacy or comorbidity	0.61 (0.46–0.81)	0.42 (0.13–1.14)	0.86 (0.61–1.2)	0.34 (0.18–0.63)
Treatment failure	1.01 (0.82–1.26)	1.97 (1.23–3.12)	0.88 (0.63–1.22)	0.90 (0.62–1.31)
Optimized protocols	0.46 (0.33–0.63)	1.25 (0.68–2.23)	0.37 (0.22–0.62)	0.34 (0.18–0.63)

Events were expressed as per 100 person-years with 95% confidence intervals (CI).