Table 5. Overview of the commercially available ELISAs for soil-transmitted helminthiases.
Records were retrieved by a Google keyword search. A limitation of our search strategy is that records that were buried deeper in the search rankings are potentially omitted. However, we deem our approach comprehensive and inclusive for our study’s specific objectives. NA: information not available. ELISA: enzyme-linked immunosorbent assay.
| Test species | Test name | Manufacturer | Commercial kit/lab diagnosis | Analyte-detection agent | Target analyte | Diagnostic sensitivity | Diagnostic specificity |
|---|---|---|---|---|---|---|---|
| Pigs | SERASCA-Test | Laboratory of Parasitology—Ghent University | Lab diagnosis | Native Ascaris suum hemoglobin protein | IgG | 99.5% | 100% |
| MonoScreen AbELISA Ascaris suum | Bio-X Diagnostics S.A. | Commercial kit | Native Ascaris suum hemoglobin protein | IgG | Relative to SERASCA: 81,2% | Relative to SERASCA: 86,1% | |
| Humans | NovaLisa Ascaris lumbricoides IgG ELISA (& Human Anti-Ascaris lumbricoides IgG ELISA Kit) |
NovaTec Immundiagnostica (& Abcam plc.) | Commercial kit | A. lumbricoides crude extract | IgG | >95% | >95% |
| Human Ascaris lumbricoides IgG antibody ELISA kit | Arigo Biolaboratories Corporation | Commercial kit | Ascaris crude extract | IgG | 100% (95% CI: 47.82% - 100%) | 95.0% (95% CI: 87.69% - 98.62%) | |
| Ascaris IgG ELISA | Bordier Affinity Products SA | Commercial kit | Ascaris coelomic soluble antigens | IgG | 1 study: 81% | 4 studies: from 57% to 98% | |
| Human anti-Ascaris lumbricoides antibody (IgM) ELISA Kit | MyBioSource, Inc. | Commercial kit | NA | IgM | NA | NA | |
| Human anti-ascaris lumbricoides antibody(IgM) Elisa Kit | AFG Bioscience | Commercial kit | Recombinant protein: ACJ03764 | IgM | ≥82.1% | ≥85.7% |