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Dosing recommendations based on available data and expert opinion for DOACs in patients with CKD. Color guide: green – recommended; yellow – suggested; orange – very limited data, use with caution after considering risks and benefits; red – no data or formal contraindication, do not use. bid, twice daily; CrCl, creatinine clearance; LMWH, low-molecular-weight heparin; qd, once daily; RRT, renal replacement therapy.
