Table 5.
Univariable cox proportional-hazard regression analysis.
| Variable | Hazard Ratio | 95% confidence interval | p-value for trenda |
|---|---|---|---|
| Age Range (n=641) | |||
| 21–30 | 1 | REF | |
| 31–40 | 0.62 | 0.19–2.03 | 0.4 |
| 41–50 | 1.96 | 0.82–4.68 | 0.13 |
| 51–60 | 2.49 | 1.09–5.68 | 0.031 |
| 61–70 | 3.48 | 1.54–7.87 | 0.003 |
| 71–80 | 4.65 | 2.05–10.6 | <0.001 |
| 81+ | 7.45 | 3.16–17.5 | <0.001 |
| Sex (n=691) | |||
| Female (n = 148) | 1.00 | REF | REF |
| Male (n = 543) | 1.94 | 1.555–2.426 | <0.001 |
| Ethnicity (n=654) | |||
| Hispanic or Latino (n = 17) | 1.00 | REF | REF |
| Non-Spanish Non-Hispanic (n = | 1.37 | 0.7528–2.488 | 0.304 |
| 637) | |||
| Race (n=678) | |||
| Asian (n = 5) | 1.00 | REF | REF |
| Black (n = 12) | 0.80 | 0.2347–2.740 | 0.725 |
| Other (n = 8) | 0.99 | 0.2669–3.706 | 0.993 |
| White (n = 653) | 1.73 | 0.6471–4.639 | 0.274 |
| Histological Type (n=534) | |||
| Biphasic (n = 88) | 1.00 | REF | REF |
| Epithelial or epithelioid (n = 409) | 0.41 | 0.3220–0.5293 | <0.001 |
| Sarcomatoid (n = 37) | 1.06 | 0.7117–1.5676 | 0.786 |
| Anatomic Site (n=337) | |||
| Peritoneum (n = 44) | 1.00 | REF | REF |
| Pleura (n = 293) | 2.44 | 1.658–3.582 | <0.001 |
| Therapy (therapy itself =0 is the REF) (n=693) | |||
| Chemotherapy (458: 235) | 0.64 | 0.5356–0.761 | <0.001 |
| Surgery (477: 216) | 0.55 | 0.463–0.6641 | <0.001 |
| Radiation therapy (136: 557) | 0.92 | 0.7486–1.128 | 0.418 |
| Immunotherapy (49: 644) | 0.47 | 0.3183–0.6819 | <0.001 |
| Photodynamic (76: 617) | 0.92 | 0.709–1.192 | 0.526 |
| Talc Pleurodesis (23: 670) | 1.70 | 1.106–2.6 | 0.01 |
| Exposure (exposure itself =0 is the REF) (n=693) | |||
| Asbestos (426: 267) | 1.50 | 1.236–1.76 | <0.001 |
| Unknown (97: 596) | 0.88 | 0.6867–1.122 | 0.298 |
| Chemical Solvents (47: 646) | 1.10 | 0.7824–1.513 | 0.616 |
| Woodworking (23: 670) | 0.78 | 0.4586–1.326 | 0.358 |
| Rubber (12: 681) | 0.78 | 0.4044–1.511 | 0.464 |
| Leather (5: 688) | 1.10 | 0.3447–3.34 | 0.903 |
| Petroleum (17: 676) | 0.69 | 0.3686–1.288 | 0.243 |
| Painting (27: 666) | 1.30 | 0.8275–1.984 | 0.267 |
| Metal Work (30: 663) | 1.20 | 0.8304–1.856 | 0.292 |
| Printing (8: 685) | 0.55 | 0.2267–1.323 | 0.181 |
| Industry (industry itself=0 is the REF for each) (n=693) | |||
| Format: Industry (n1:n0) (n1 = YES, n0 = NO) | |||
| Agriculture, Forestry, Fishing and Hunting (9: 684) | 0.66 | 0.3114–1.384 | 0.269 |
| Mining, Quarrying, and Oil and Gas Extraction (15: 678) | 1.00 | 0.5845–1.839 | 0.902 |
| Utilities (24: 669) | 1.10 | 0.6431–1.74 | 0.825 |
| Construction (113: 580) | 1.30 | 1.042–1.606 | 0.020 |
| Manufacturing (188: 505) | 1.20 | 0.992–1.431 | 0.061 |
| Wholesale Trade (7: 686) | 0.34 | 0.1107–1.071 | 0.066 |
| Retail Trade (40: 653) | 0.57 | 0.3816–0.8659 | 0.008 |
| Transportation and Warehousing (46: 647) | 1.00 | 0.7429–1.437 | 0.847 |
| Information (14: 679) | 0.86 | 0.4729–1.562 | 0.619 |
| Finance and Insurance (20: 673) | 0.67 | 0.3915–1.132 | 0.133 |
| Real Estate and Rental and Leasing (12: 681) | 0.74 | 0.3819–1.427 | 0.367 |
| Professional, Scientific, and Technical Services (53: 640) | 0.75 | 0.5406–1.03 | 0.075 |
| Administrative and Support and Waste Management and Remediation Services (23: 670) | 0.99 | 0.6116–1.608 | 0.973 |
| Educational Services (57: 636) | 1.00 | 0.7348–1.37 | 0.984 |
| Health Care and Social Assistance (55: 638) | 0.55 | 0.3945–0.7718 | <0.001 |
| Arts, Entertainment, and Recreation (10: 683) | 0.69 | 0.3282–1.46 | 0.334 |
| Accommodation and Food Services (24: 669) | 0.58 | 0.3465–0.9732 | 0.039 |
| Other Services (except Public | 0.81 | 0.5662–1.157 | 0.246 |
| Administration) (48: 645) | |||
| Public Administration (52: 641) | 1.10 | 0.7723–1.495 | 0.670 |
| Military (54: 639) | 1.00 | 0.7532–1.425 | 0.828 |
(Categories with less than 5 records are not included in the table. REF is the reference group.)
a
p-value has not been adjusted here. Each patient was compared multiple times for the industry, therapy, and exposure; therefore, type I error may increase.