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Labeling of NeuN (green) and GFAP (red) in the CA3 hippocampal region of SAMR-1 (A–D), SAMP-8 (E–H) and SAMP-8 Li (I–L). Cellular nuclei were labeled with DAPI (blue). Images were obtained using an inverted DMi8 microscope (Leica, Wetzlar, Germany) with a 10× objective. Scale bar: 100μm. M and N: Percentage of NeuN and GFAP labeling in the CA3 area of the three groups. Histograms and vertical bars are means ± SEM of samples from 5 animals per group. *: p < 0.05.
