Table 4.
Comparison of different outcomes for each subgroup by assigned treatment
| Subgroup x treatment | MADRS at baseline, mean (SD) | MADRS at week 8, mean (SD) |
Mean change (%, SD) |
Response at week 8, % | Remission at week 8, % |
|---|---|---|---|---|---|
| Be ESC/CM|Tr ESC/CM; n = 12 | 30.1 (6.9) | 15.1 (11.2) | −50.9 (35.4) | 58.3 | 33.3 |
| Be CBASP|Tr CBASP; n = 10 | 26.8 (8.5) | 17.5 (6.9) | −33.3 (22.3) | 20.0 | 10.0 |
| Be CBASP|Tr ESC/CM; n = 12 | 22.3 (8.9) | 22.4 (9.4) | 6.9 (37.3) | 8.3 | 8.3 |
| Be ESC/CM|Tr CBASP; n = 16 | 27.2 (9.0) | 27.3 (8.4) | 5.0 (28.7) | 0.0 | 0.0 |
|
Be ESC/CM|Tr ESC/CM + Be CBASP|Tr CBASP; n = 22 |
28.6 (7.6) | 16.2 (9.4) | −42.9 (30.8) | 40.9 | 22.7 |
|
Be ESC/CM|Tr CBASP + Be CBASP|Tr ESC/CM; n = 28 |
25.1 (9.1) | 25.2 (9.0) | 5.8 (32.0) | 3.6 | 3.6 |
Abbreviations: Be [treatment condition] = likely higher benefit from this treatment condition; CBASP, Cognitive Behavioral Analysis System of Psychotherapy; ESC/CM, escitalopram plus clinical management; MADRS, Montgomery-Asberg Depression Rating Scale [48]; SD, standard deviation, Tr [treatment condition]= treated with this treatment condition