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. 2024 Feb 6;39(3):289–298. doi: 10.1007/s10654-024-01104-w

Table 2.

Prevalence of childhood atopic medication purchases in ages 0–15 (%) by (A) birth order and number of siblings for the full population and (B) age difference with second-born sibling for first-born children. Birth cohorts 1995–2004

N Antihistamines Eczema medication Asthma medication Epinephrine
A) Birth order (#) by number of children in the family
#1/1 88 481 43.1 33.3 20.0 2.8
#1/2 112 893 42.7 33.5 20.1 3.4
#2/2 111 258 38.1 31.6 18.1 2.8
#1/3 46 389 39.3 31.6 18.7 3.3
#2/3 48 000 34.6 29.3 17.1 2.6
#3/3 51 630 33.4 28.4 15.3 2.3
#1/4+ 19 113 32.8 28.1 15.6 2.5
#2/4+ 19 237 29.5 26.7 15.3 2.2
#3/4+ 20 888 27.4 25.8 14.9 2.0
#4+/4+ 41 188 23.7 23.9 13.0 1.4
Total 559 077 37.2 30.7 17.8 2.8
B) First-born’s age difference with second-born
Twins 9 237 37.0 28.4 20.6 2.3
1 year 21 650 35.7 30.3 16.9 2.6
2 years 66 300 40.1 32.5 18.6 3.5
3 years 39 629 42.4 32.9 20.1 3.4
4 years 18 831 43.4 33.8 20.2 3.4
5 + years 22 748 43.7 33.7 20.6 3.4
Only child 88 481 43.1 33.3 20.0 2.9
Total 266 876 41.5 37.7 19.5 3.2