Fig 5.
Adult locomotor activity in an open field after saline treatment on the first acclimation day (A-D) and change in activity due to nicotine treatment (E-H). Nicotine locomotor depression is represented by the difference in distance traveled between the second day of testing (after saline) and the third day of testing (after nicotine; see methods section for details). Data are shown as mean +/− SEM. n=13–16 per strain per sex per group. Sex by treatment interactions were detected for Day 1 locomotor activity.