Table 1.
Baseline characteristics of the original population.
| Vitamin D | No vitamin D | p | |
|---|---|---|---|
| N | 587 | 2,616 | |
| Age (years) | 72 (63,79) | 72 (64,80) | 0.5 |
| Gender, n | |||
| Female | 297 | 1,223 | 0.09 |
| Male | 290 | 1,393 | |
| Weight (kg) | 82 (66,100) | 78 (64,95) | 0.009 |
| Vital signs | |||
| HR | 84 (74,97) | 83 (74,96) | 0.4 |
| MAP, mmHg | 76 (70,83) | 77 (71,84) | 0.3 |
| Respiratory rate (breaths/min) | 19 (17,22) | 19 (17,22) | 0.84 |
| Temperature (°C) | 37 (36,37) | 37 (36,37) | 0.9 |
| SpO2, % | 96 (94,97) | 96 (95,98) | <0.001 |
| Laboratory parameters | |||
| Hemoglobin, g/dL | 10 (9,11) | 10 (9,12) | <0.001 |
| RBC count, 109/L | 3.7 (3.2,4.1) | 3.7 (3.2,4.2) | 0.06 |
| Hematocrit, % | 32 (27,36) | 32 (28,37) | 0.003 |
| Platelet, 109/L | 200 (146,257) | 191 (141,252) | 0.1 |
| WBC count, 109/L | 11 (8,15) | 12 (9,15) | 0.2 |
| Anion gap, mg/dL | 15 (13,17) | 15 (12,17) | 0.5 |
| Bicarbonate, mg/dL | 24 (21,28) | 24 (21.27) | 0.01 |
| Bun, mg/dL | 24 (16,42) | 22 (15,36) | 0.001 |
| Calcium, mg/dL | 9 (8,9) | 8 (8,9) | 0.005 |
| Chloride, mmol/L | 101 (96,105) | 102 (98,105) | <0.001 |
| Creatinine mg/dL | 1.1 (0.8,1.9) | 1.1 (0.8,1.6) | 0.01 |
| Glucose, mmol/L | 137 (109,170) | 132 (110,163) | 0.2 |
| Sodium, mg/dL | 139 (135,141) | 139 (136,141) | 0.4 |
| Potassium, mg/dL | 4.3 (4.0,4.8) | 4.4 (4,4.8) | 0.4 |
| INR | 1.3 (1.1,1.5) | 1.3 (1.1,1.5) | 0.02 |
| PT | 14 (12,16) | 14 (12,16) | 0.03 |
| Severity of illness | |||
| SOFA score | 5 (2,8) | 5 (3,8) | 0.8 |
| APS III score | 48 (37,63) | 46 (34,62) | 0.008 |
| OASIS | 32 (27,39) | 33 (27,40) | 0.06 |
| Comorbidities | |||
| Myocardial infarct, n | 132 | 690 | 0.05 |
| Congestive heart failure, n | 340 | 1,269 | <0.001 |
| Rheumatic disease, n | 37 | 118 | 0.07 |
| Peptic ulcer disease, n | 17 | 77 | 0.4 |
| Liver disease, n | 60 | 236 | 0.9 |
| Diabetes, n | 250 | 959 | 0.007 |
| Renal disease, n | 212 | 760 | 0.001 |
| Malignant cancer, n | 86 | 386 | 0.9 |
| Ventilator use, n | 167 | 995 | <0.001 |
| RRT use, n | 46 | 117 | 0.001 |
| Vasopressor use, n | 45 | 255 | 0.5 |
| Mortality | |||
| In-hospital mortality, n | 63 | 372 | 0.03 |
| ICU-mortality, n | 33 | 259 | 0.001 |
INR, international normalized ratio; PT, prothrombin time; RRT, renal replacement therapy.