Table 3.
Overall survival according to physical activitya
| Total n | Incidence 1 y (1 y survival probability) | HRcrude (95% CI) | HRadj, excl-ECOG (95% CI) | HRadj, ECOG (95% CI) | |
|---|---|---|---|---|---|
| Total PA (MET-hours/week) | P = .019a | P = .279a | |||
| Low | 84 | 25 (0.68) | – | – | – |
| Moderate | 83 | 12 (0.83) | 0.51 (0.29 to 0.90) | 0.58 (0.32 to 1.04) | 0.69 (0.37 to 1.29) |
| High | 84 | 9 (0.88) | 0.42 (0.24 to 0.76) | 0.48 (0.27 to 0.89) | 0.60 (0.32 to 1.11) |
| MVPA-SL (hours/week) | P = .036a | P = .192a | |||
| Zero | 54 | 25 (0.68) | – | – | – |
| Low | 94 | 12 (0.83) | 0.51 (0.29 to 0.90) | 0.58 (0.32 to 1.04) | 0.73 (0.40 to 1.34) |
| High | 103 | 9 (0.88) | 0.42 (0.24 to 0.76) | 0.48 (0.27 to 0.89) | 0.48 (0.24 to 0.96) |
a
Likelihood ratio test P value for multivariable model with PA using restricted cubic splines versus model without PA. PA = physical activity; MVPA-SL = moderate- to vigorous-intensity physical activity during sports and leisure time in hours per week; MET = metabolic equivalent task; HRcrude = unadjusted hazard ratio; HRadj = odds ratio adjusted for sex, age, tumor type, setting, previous systemic therapy, type of therapy, and in case of HRadj, ECOG Eastern Cooperative Oncology Group performance status.