Table 1.
Clinical characteristics of MS patients at baseline.
RR-MS (76) | |
---|---|
Age, years (mean, SD) | 34.6 ± 10.3 |
Sex, F/M (N, %) | 59/17 (77.6) |
Disease duration, months (median, IQR) | 3.6 (1.2–19.3) |
Radiological activity (1 = yes, 0 = no) (N/tot (%)) | 37/74 (50)* |
EDSS (median, IQR) | 1.5 (1–2) |
MSSS (median, IQR) | 3.9 (2.9–6.5) |
LCVA at 2.5% (median, IQR) | 43 (38–45) |
LCVA at 1.25% (median, IQR) | 37 (32–42) |
CSF IL-10 (pg/mL) (mean, SD) | 2.3 ± 1.8 |
DMT (0 = platform, 1 = high efficacy) (N, %) | 52/24 (68.4) |
SD, standard deviation; N, number; IQR, interquartile range; EDSS, Expanded Disability Status Scale; MSSS, Multiple Sclerosis Severity Scale; LCVA, low-contrast visual acuity; CSF, cerebrospinal fluid; DMT, disease-modifying therapies; platform therapies: interferon beta-1a 30 mcg = 1 patient; interferon beta-1a 22 mcg = 4 patients; interferon beta-1a 44 mcg = 1 patient; peginterferon beta-1a = 3 patients; teriflunomide = 3 patients; glatiramer acetate = 11 patients; dimethyl fumarate = 29 patients; total 52; high-efficacy therapies (ocrelizumab = 2 patients; cladribine = 5 patients; fingolimod = 10 patients; natalizumab = 6 patients; rituximab = 1 patient; total 24). *Missing data for 2 patients.