Table 3.
Intraclass correlation coefficients (ICCs) for the correspondence between low-field (64mT) and high-field (3T) MR images and comparisons across super-resolution approaches.
| Brain measure | Standard Axial 64mT ICCs with 3T | SynthSR-Processed Axial 64mT ICCs with 3T | Steiger’s | ||||||
|---|---|---|---|---|---|---|---|---|---|
| ICC | p | q | ICC | p | q | Z | p | q | |
| Total Surface Area | 0.71 | 1.65e-12 | 4.15e-12 | 0.90 | 2.55e-26 | 1.46e-25 | 4.35 | 1.38e-05 | 2.41e-05 |
| Mean Cortical Thickness | −0.05 | 0.668 | 0.701 | 0.13 | 0.139 | 0.178 | 1.29 | 0.197 | 0.230 |
| Estimated Intracranial Volume | 0.79 | 1.11e-16 | 3.04e-16 | 0.84 | 2.68e-20 | 1.06e-19 | 2.07 | 0.038 | 0.053 |
| Subcortical Gray Matter Volume | 0.66 | 1.46e-10 | 3.40e-10 | 0.88 | 1.14e-24 | 6.01e-24 | 4.57 | 4.81e-06 | 9.17e-06 |
| Cortical Volume | 0.61 | 1.08e-08 | 2.34e-08 | 0.82 | 1.32e-18 | 4.38e-18 | 4.06 | 4.91e-05 | 8.36e-05 |
| Cerebral White Matter Volume | 0.24 | 0.024 | 0.036 | 0.91 | 5.44e-29 | 3.43e-28 | 8.47 | 2.42e-17 | 7.34e-17 |
| Total Brain Volume | 0.56 | 1.43e-07 | 2.90e-07 | 0.97 | 1.49e-42 | 2.35e-41 | 9.40 | 5.49e-21 | 2.30e-20 |
| Brain measure | Standard Axial 64mT ICCs with 3T | Standard Multi-Orientation 64mT ICCs with 3T | Steiger’s | ||||||
| ICC | p | q | ICC | p | q | Z | p | q | |
| Total Surface Area | 0.71 | 1.65e-12 | 4.15e-12 | 0.58 | 7.44e-08 | 1.56e-07 | −1.88 | 0.059 | 0.080 |
| Mean Cortical Thickness | −0.05 | 0.668 | 0.701 | −0.22 | 0.969 | 0.969 | −1.32 | 0.187 | 0.223 |
| Estimated Intracranial Volume | 0.79 | 1.11e-16 | 3.04e-16 | 0.76 | 7.51e-15 | 1.97e-14 | −1.94 | 0.052 | 0.072 |
| Subcortical Gray Matter Volume | 0.66 | 1.46e-10 | 3.40e-10 | 0.71 | 2.32e-12 | 5.61e-12 | 0.91 | 0.360 | 0.398 |
| Cortical Volume | 0.61 | 1.08e-08 | 2.34e-08 | 0.49 | 7.32e-06 | 1.36e-05 | −1.53 | 0.126 | 0.165 |
| Cerebral White Matter Volume | 0.24 | 0.024 | 0.036 | 0.30 | 0.006 | 0.010 | 2.11 | 0.035 | 0.051 |
| Total Brain Volume | 0.56 | 1.43e-07 | 2.90e-07 | 0.66 | 1.98e-10 | 4.46e-10 | 3.38 | 7.27e-04 | 0.001 |
| Brain measure | Standard Axial 64mT ICCs with 3T | SynthSR-Processed Multi-Orientation 64mT ICCs with 3T | Steiger’s | ||||||
| ICC | p | q | ICC | p | q | Z | p | q | |
| Total Surface Area | 0.71 | 1.65e-12 | 4.15e-12 | 0.87 | 3.67e-23 | 1.78e-22 | 3.50 | 4.72e-04 | 7.62e-04 |
| Mean Cortical Thickness | −0.05 | 0.668 | 0.701 | 0.12 | 0.160 | 0.194 | 1.07 | 0.282 | 0.324 |
| Estimated Intracranial Volume | 0.79 | 1.11e-16 | 3.04e-16 | 0.83 | 2.01e-19 | 7.04e-19 | 1.45 | 0.147 | 0.185 |
| Subcortical Gray Matter Volume | 0.66 | 1.46e-10 | 3.40e-10 | 0.86 | 2.58e-22 | 1.16e-21 | 3.91 | 9.17e-05 | 1.52e-04 |
| Cortical Volume | 0.61 | 1.08e-08 | 2.34e-08 | 0.84 | 5.64e-20 | 2.09e-19 | 4.45 | 8.54e-06 | 1.54e-05 |
| Cerebral White Matter Volume | 0.24 | 0.024 | 0.036 | 0.92 | 2.41e-29 | 1.69e-28 | 8.47 | 2.45e-17 | 7.34e-17 |
| Total Brain Volume | 0.56 | 1.43e-07 | 2.90e-07 | 0.96 | 1.56e-38 | 1.64e-37 | 8.43 | 3.42e-17 | 9.80e-17 |
Top section: Left column shows ICC values between standard single low-field (64mT) and high-field (3T) images for each brain measure. Middle column shows ICCs between SynthSR-processed low-field and high-field estimates. Right column shows results of Steiger Z-tests, assessing whether the ICCs for standard and SynthSR-processed scans are statistically different. Middle section: Left column shows ICCs between standard single low-field (64mT) and high-field (3T) images for each brain measure. Middle column shows ICCs between standard multi-orientation low-field and high-field estimates. Right column shows results of Steiger Z-tests, assessing whether the ICCs for single and multi-orientation approaches are statistically different. Bottom section: Left column shows ICCs between standard single low-field (64mT) and high-field (3T) images for each brain measure. Middle column shows ICCs between SynthSR-processed multi-orientation low-field and high-field estimates. Right column shows results of Steiger Z-tests, assessing whether the ICCs for standard and SynthSR-processed multi-orientation approaches are statistically different. Values in bold survive correction for multiple comparisons.