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. Author manuscript; available in PMC: 2024 Apr 5.
Published in final edited form as: Neuron. 2023 Nov 8;111(23):3710–3715. doi: 10.1016/j.neuron.2023.09.029

Table 1.

Major characteristics of three successful data-sharing processes developed for invasive human electrophysiology within the NIH Research Opportunities in Humans (ROH) Consortium

Restoring Active Memory (RAM) project: Michael Kahana Laboratory, University of Pennsylvania, and partners Memory Intracranial Neural Dynamic (MIND) project: Ueli Rutrshauser Laboratory, Cedars-Sinai Medical Center, and partners High-resolution single-unit recordings of cortical neurons dataset: Laboratories at Harvard Medical School and Massachusetts General Hospital
Population patients with refractory epilepsy patients with refractory epilepsy participants undergoing clinical intraoperative physiological recordings
Data type(s) • electrocorticographic recordings
• patient demographics
• individual electrode contact atlas location and coordinates for localization
• FreeSurfer files
• D-cortical surface renderings
• seizure onset zones
• interictal spiking
• behavioral event data for ten different memory tasks
• open- and closed-loop brain stimulation tasks
• Electrophysiological recordings (single neurons and local field potentials)
• patient demographics
• behavior
• task stimulus
• task event timestamps
• electrode locations
• high-resolution laminar recordings
Format(s) BIDS NWB • SpikeGLX
• OpenEphys
Archive(s) University-hosted webpage DANDI
DABI
Dryad
Strategies for data sharing • standardized file formats • standardized file formats
• outreach to unique users
• publication and use of open-source software
• standardized file formats
• publication and use of open-source software
Selected ways data have been reused • education, training
• analytical tool development
• outreach, education, and training
• analytical tool development
• scientific discovery (research)
• analytical tool development
• raw data export and analysis
Benefits for data generator • earty-stage investigator training and career advancement
• reanalysis of existing data
• facile dataset curation
• resolution of technical issues
• enhanced lab productivity
• identification of collaboration opportunities
• facilitates reanalysls of existing data
• use in teaching
• stimulated interest in intra-species comparison of brain
• multidisciplinary collaboration