Figure 2.

H67D mice perform better on rotarod 3 d after intracerebral hemorrhage (ICH) compared with wild-type (WT).

Functional motor recovery was measured by latency to fall from rotarod. H67D mice (n=24, mean, 48.8, SD=23.81) initially display no differences in functional recovery at day 1 poststroke when compared with WT (n=24, mean, 58.00, SD=18.63; P=0.134). However, at day 2 (H67D: mean, 73.04, SD=21.53; WT: mean, 55.16, SD=21.08; P=0.0047) and 3 poststroke (H67D: mean, 82.96, SD=32.16; WT: mean, 58.8, SD=24.88; P=0.0046), H67D mice are significantly less vulnerable to falling when compared with WT. Error bars reported as SD, *P<0.05, **P<0.001.