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. 2024 Apr 5;24:420. doi: 10.1186/s12885-024-12107-x

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Identification of vasculogenic mimicry-related isoforms. (A) Clustering heat map of ccRCC divided into two clusters. PCA analysis (B), survival curves (C) and clinical shapes (D) were analyzed between the two clusters. Heatmaps of enrichment in HALLMARK pathway (E), KEGG (F) and GO (G) pathway enrichment between the two clusters were identified by enrichment analysis. (H) Tumor purity, ESITIMATE score, immune score and stroma score between the two clusters. (I) Comparison of differences in immune function and immune cell infiltration levels between the two clusters by ssGSEA. (J) Analysis of common immune checkpoint differences between the two clusters. Note * p < 0.05, **p < 0.01, ***p < 0.001