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. 2024 Apr 5;24:119. doi: 10.1186/s12866-024-03278-5

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Structure and differential enrichment analysis of gut microbial communities in obesity. A, B, C Comparison of α diversity (Shannon index; A), β diversity (Bray-Curtis similarity index; B) and gene richness(C) of microbial content between the obesity and the control group. D PCoA analysis based on Bray-Curtis distance, with PERMANOVA used to assess differences in bacterial composition between the obesity and control groups. E Relative abundance of the top 10 bacterial phyla. F Relative abundance of the top 10 bacterial genera. G Differentially enriched species obtained through MAssLin2 analysis (p < 0.01, FDR < 0.01), with bacterial species names marked with “*” indicating consistency with LEfSe analysis results (LDA > 2, p < 0.05). The x axis represents the coefficient value calculated by MaAsLin2 analysis