Table 2.
Diagnostic performance of rad-score and nomogram model in the primary and validation cohorts
| Cohorts | AUC | SEN | SPE | +LR | -LR | PPV | NPV |
|---|---|---|---|---|---|---|---|
| Rad-score in primary cohort | 0.76 (0.69–0.83) |
0.68 (0.58–0.77) |
0.75 (0.60–0.86) |
2.72 (1.6–4.5) |
0.43 (0.3–0.6) |
0.86 (0.78–0.91) |
0.51 (0.43–0.59) |
| Nomogram in primary cohort | 0.78 (0.71–0.84) |
0.90 (0.82–0.95) |
0.58 (0.43–0.72) |
2.15 (1.5–3.0) |
0.18 (0.1–0.3) |
0.83 (0.77–0.87) |
0.72 (0.58–0.82) |
| Rad-score in validation cohort | 0.81 (0.70–0.89) |
0.84 (0.71–0.94) |
0.71 (0.53–0.85) |
2.87 (1.7–4.9) |
0.22 (0.1–0.5) |
0.79 (0.69–0.87) |
0.77 (0.63–0.88) |
| Nomogram in validation cohort | 0.82 (0.72–0.90) |
0.80 (0.65–0.90) |
0.77 (0.59–0.89) |
3.40 (1.8–6.3) |
0.26 (0.1–0.5) |
0.82 (0.71–0.89) |
0.74 (0.61–0.84) |
AUC: area under the curve;+LR: positive likelihood ratio; -LR: negative likelihood ratio; NPV: negative-predictive value; PPV: positive-predictive value; SEN: sensitivity; SPE: specificity.