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[Preprint]. 2024 Oct 1:2024.03.24.586457. Originally published 2024 Mar 27. [Version 2] doi: 10.1101/2024.03.24.586457

Fig 1. Silent synapses are upregulated in the dorsolateral striatum under chronic HFD.

Fig 1.

A) Feeding paradigm for chow and HFD mice (top) and weight changes over time (bottom). B) Minimal stimulation assay (left) and the percentage of silent synapses (right) of dMSNs and iMSNs in chow and HFD-fed mice. C) Cumulative probability of amplitude (pA) (left) and interevent interval (ms) (right) in dMSN and iMSNs. D) Example traces of gap-free mEPSCs with 50 μM picrotoxin and 10 μM TTX. Data are presented as mean ± SEM. *p< 0.05.