Fig 4. HFD reduces stubby dendritic spines in the indirect pathway.

A) Representative images of iMSN-GFP neurons (left), DiI only (middle), and the overlap of iMSN-GFP and DiI labelling (right). B) Representative images of dendritic branch in dMSNs and iMSNs. C) Representative examples of different spine subtypes. D) Number of spines per μm of sampled dendritic branch including all spine subtypes (left) and broken down by individual spine subtype (right 4 graphs). Data are presented as mean ± SEM. *p< 0.05.