Table 2.
Comparisons for each parameter between homozygous individuals for the reference allele, heterozygous and homozygous for the rs6190 alternative allele in the UK Biobank male population.
| Parameter, N | REF | HET | P-value vs REF | HOMO | P-value vs REF |
|---|---|---|---|---|---|
| Age in years | 58 (58 – 58) | 58 (58 – 59) | 0.1638 | 58 (56 – 59) | >0.9999 |
| N | 210446 | 11811 | 191 | ||
| Glycemia in mM | 4.956 (4.953 – 4.959) | 4.926 (4.915 - 4.937) | <0.0001 | 4.881 (4.793 - 4.980) | 0.0218 |
| N | 183988 | 9657 | 159 | ||
| BMI in kg/m2 | 27.30 (27.28 - 27.32) | 27.29 (27.21 - 27.38) | 0.0517 | 26.95 (25.99 - 27.71) | 0.0469 |
| N | 209459 | 11556 | 178 | ||
| Hand grip strength/lean arm mass in kg/kg | 11.58 (11.56 - 11.58) | 11.56 (11.50 - 11.61) | 0.9477 | 11.95 (11.37 - 12.35) | 0.0636 |
| N | 205953 | 11544 | 178 | ||
| Lean mass in % of body mass | 74.64 (74.61 - 74.66) | 74.61 (74.46 - 74.73) | >0.9999 | 75.85 (74.66 - 76.77) | 0.0622 |
| N | 206356 | 11582 | 184 |
Values are presen ed as median (95% CI); Kruskal-Wallis test with Dunn’s multiple comparison. P-values lower or close to 0.05 were highlighted in bold.