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. 2022 Jun 15;95(1137):20211211. doi: 10.1259/bjr.20211211

Table 1.

Description of RQS parameters

Parameters Marks
 1  Image protocol: recorded image protocols in detail (+1) and/or general utilization for reproducibility (+1).  0 _ 2
2 Multiple segmentation: Multiple segmentation is done by different fellows or made by different applications (+1). To study feature validity at different segmentation modules. 0, 1
3
4
5
6
7
8
9
10
11
12
13
14
15
16
Phantom study: To study features validity, a phantom study is an origin of diversity on the scanners (+1).
Multiple time points: Images at different time points - multiple images for treatment and/or pre-treatment follow-up (+1). To study features validity at different time points.
Feature reduction: To study features validity by feature selection, feature reduction accommodates features for multiple trials. It prevents the selection of corresponding features for a set of samples.
Non-Radiomics: Non-Radiomics features represent an integrated Radiomic study to find the potential correlations between Non-Radiomics and Radiomics features (+1).
Biological correlates: identifying biological correlation provides insight into the biological correspondence with Radiomics (+1).
Cut-off: cut-off investigations identify risk factors or at-risk populations using statistical analyses (+1).
Discrimination and resampling: based on the results of statistical analyses, discrimination is determined by the ROC curve, AUC, concordance statistic. Statistical significance is determined by P-value, confidence interval (+1). The resampling method can be utilized by cross-validation and bootstrap techniques in statistics (+1).
Calibration: calibration statistics are used in predictive analytics by calibration slope, calibration plot, calibration in the large, and determining the statistical significance by P-value, confidence interval (+1). The resampling method can be utilized by cross-validation and bootstrap techniques in statistics (+1).
Prospective: prospective models are used in the trial studies for validation of clinical prediction models to determine the application of specific radiomic biomarkers (+7).
Validation: validation is an established set of data from the same institute (+2), from another institute (+3), two separate institutes (+4), a published study in the past (+4), and three or more separate institutes (+5), or lack of validation (−5).
Gold standard: it determines which model in the Radiomic study is in concordance with the gold standard model (+2).
Clinical utility: it determines whether the Radiomic study is potentially useful (+1) or currently active (+1) in clinical applications.
Cost-effectiveness: it determines whether the Radiomic study is valuable and cost-effective in clinical applications (+1).
Open science: making encoded data available for public and open encrypted data, promotes consistency and the ability to reproduce the study. Open source of scans (+1), open-source of ROI segmentation (+1), open-source of code (+1), calculation radiomic features based on a typical set of ROIs and ROIs are open source (+1).
0, 1
0, 1
−3, + 3
0, 1
0, 1
0, 1
0 _ 2
0 _ 2
0, + 7
−5, 2 _ 5
0, + 2
0 _ 2
0, 1
0 _ 4