Table 2.

The summary of findings table with the certainty of the rankings using the GRADE minimally-contextualized framework.

Change in HbA1c	Change in FPG	Change in Body Weight	Severe Hypoglycemia	Overall Hypoglycemia	Nocturnal Hypoglycemia
IDeg-200	IDeg-3TW	IGlar-300	IDeg-100	IDeg-100	IDeg-100
IDeg-100	IDeg-100	IGlar-100	IDeg-200	IDeg-200	IDeg-200
IDeg-3TW	IDeg-200	ILPS	IGlar-300	IDet	IDet
IDet	IGlar-100	IDet	IDet	IDeg-3TW	IDeg-3TW
NPH	IGlar-300	IDeg-100	IGlar-100	IGlar-300	IGlar-300
IGlar-300	IDet	IDeg-200	IDeg-3TW	IGlar-100	IGlar-100
IGlar-100	ILPS	NPH	NPH	ILPS	ILPS
ILPS	NPH	IDeg-3TW	ILPS	NPH	NPH
High to Moderate Certainty Evidence			Low to Very Low Certainty Evidence
Among the most effective/least harmful			Possibly among the most effective
Not convincingly different from standard treatment (IGlar-100)			Possibly not convincingly different from standard treatment (IGlar-100)
Among the most harmful/least effective			Possibly among the most harmful/least effective