Table 2. Associations^* of the plasma omega-6/omega-3 PUFAs ratio with all-cause, cancer, and CVD mortality risk in the UK Biobank.

Omega ratio variable forms	Causes of death
	All-cause			Cancer			Cardiovascular diseases
	Number of deaths	Partially adjusted associations†	Fully adjusted associations‡	Number of deaths	Partially adjusted associations†	Fully adjusted associations‡	Number of deaths	Partially adjusted associations†		Fully adjusted associations‡
		HR(95%CI)	HR(95%CI)		HR(95%CI)	HR(95%CI)		HR(95%CI)	HR(95%CI)
Continuous	6461	1.02 (1.02–1.03)	1.02 (1.02–1.03)	2794	1.02 (1.01–1.03)	1.01 (1.00–1.02)	1668	1.02 (1.01–1.03)	1.02 (1.01–1.03)
Quintiles (median)
1 (5.9)	1348	1.00 (ref)	1.00 (ref)	593	1.00 (ref)	1.00 (ref)	369	1.00 (ref)	1.00 (ref)
2 (7.6)	1256	1.00 (0.92–1.08)	0.96 (0.88–1.05)	563	1.02 (0.91–1.15)	0.98 (0.86–1.12)	315	0.90 (0.77–1.05)	0.89 (0.75–1.06)
3 (9.1)	1236	1.06 (0.98–1.15)	1.01 (0.93–1.11)	543	1.08 (0.96–1.21)	0.99 (0.87–1.13)	321	0.97 (0.84–1.13)	0.97 (0.81–1.16)
4 (11.0)	1252	1.14 (1.06–1.23)	1.09 (1.00–1.19)	548	1.16 (1.03–1.31)	1.12 (0.98–1.27)	306	0.98 (0.84–1.15)	1.02 (0.86–1.22)
5 (14.8)	1369	1.34 (1.24–1.45)	1.26 (1.15–1.38)	547	1.27 (1.12–1.43)	1.14 (1.00–1.31)	357	1.20 (1.04–1.40)	1.31 (1.10–1.55)
P trend		<0.001	<0.001		<0.001	0.011		0.002	<0.001

^*From Cox proportional hazards regression.

^†Adjusted for age (years; continuous), sex (male, female), race (White, Black, Asian, Others), Townsend deprivation index (continuous), assessment centre.

^‡Adjusted for age (years; continuous), sex (male, female), race (White, Black, Asian, Others), Townsend deprivation index (continuous), assessment centre, BMI (kg/m2; continuous), smoking status (never, previous, current), alcohol intake status (never, previous, current), physical activity (low, moderate, high), and comorbidities (yes, no).

CI, confidence interval; HR, hazards ratio; ref, reference.