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. Author manuscript; available in PMC: 2025 Jun 1.
Published in final edited form as: Magn Reson Med. 2024 Jan 19;91(6):2597–2611. doi: 10.1002/mrm.29996

Table 2. Parameters of the biophysical THB model.

(A) Results of fitting the theoretical expression for R1W, Eq. (27), to the data in Table 1. Numbers represent fitting parameters ± fitting errors. (B) Detail biophysical parameters of THB model. Data represent estimates of parameters nTR,λ,dH using data for the fast T1 component [65] (not available for Globus Pallidum), the theoretical equations for R1H and R1W, Eq. (14), and the expression for λ. Eq. (24). In both cases, A and B, the uniform orientation distribution of vectors r, Eq. (34), is used.

A WM cGM Caudate Thalamus Putamen Glob. Pall.
nTRλ (s−1) 4.43 ± 0.37 3.19 ± 1.26 2.82 ± 0.31 2.90 ± 0.26 2.99 ± 0.29 3.45 ± 0.32
τ (ns) 2.51 ± 0.19 4.96 ± 3.52 3.49 ± 0.49 2.75 ± 0.26 3.06 ± 0.35 2.47 ± 0.18
b 0.56 ± 0.08 0.42 ± 0.18 0.57 ± 0.09 0.58 ± 0.08 0.56 ± 0.08 0.68 ± 0.13
r1W (s−1) 0.23 ± 0.11 0.08 ± 0.22 0.27 ± 0.07 0.27 ± 0.07 0.24 ± 0.07 0.37 ± 0.10
B
nTR 0.07 0.04 0.03 0.04 0.04
λ/τ (1/s/ns) 25.74 15.96 29.35 29.46 27.56
dH (Å) 1.58 1.71 1.55 1.55 1.56