Fig. 5. Possible scenarios for the origin of Ivory Coast ace-1 duplications.

Scenario 1 requires several independent duplication events on the same breakpoints, whereas scenario 2 considers a first duplication event followed by secondary recombinations occurring in the amplicon that bears the S copy (either the whole amplicon, or only the part containing the ace-1 locus, or any size between). NB: the alleles presented here are for illustration only, as the present study did not allow firmly distinguishing the two scenarios, or any secondary recombination span. Similarly, the oblique lines are used to illustrate the recombination events, but not a particular molecular mechanism.