Table 1.
miRNA and gene expression microarray and RNA-seq datasets related to Hypersensitivity Pneumonitis. *Samples of other ILDs that were not HP and IPF were excluded. +Samples that did not approve the quality analysis were excluded.
| RNA type | Accession number of the dataset | Platform | Sample type | Experiment type | Disease type |
Number of differentially expressed genes | Reference | ||
|---|---|---|---|---|---|---|---|---|---|
| Ctrl | HP | IPF | |||||||
| miRNA | GSE21394 | Agilent-019118 Human miRNA Microarray 2.0 G4470B | Lung tissue | Non-coding RNA profiling by array | 6 | 2 | 9 | HP vs CTRL = 23 | Cho J et al., BioMed Central, 2011* |
| HP vs IPF = 31 | |||||||||
| IPF vs CTRL = 65 | |||||||||
| mRNA | GSE21369 | Affymetrix U133 plus 2.0 Array | Lung tissue | Expression profiling by array | 5 | 2 | 7 | HP vs CTRL = 317 | Cho J et al., BioMed Central, 2011*+ |
| HP vs IPF = 118 | |||||||||
| IPF vs CTRL = 261 | |||||||||
| mRNA | – | Affymetrix U133 plus 2.0 Array | Lung tissue | Expression profiling by array | – | 12 | 15 | HP vs IPF = 809 | Selman M et al., Am J Respir Crit Care Med, 2006 |
| mRNA | GSE150910 | Illumina NovaSeq 6000 (Homo sapiens) | Lung tissue | Expression profiling by RNA-seq | 103 | 82 | 103 | HP vs CTRL = 2198 | Furusawa H et al. Am J Respir Crit Care Med, 2020 |
| HP vs IPF = 569 | |||||||||
| IPF vs CTRL = 1928 | |||||||||