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. 2023 Jul 19;14(1):241–252. doi: 10.34172/apb.2024.002

Table 3. Hematological parameters of rats with arthritis induced by Freund’s Complete Adjuvant (FCA) on day 28 after the injection of FCA (after two weeks of treatment) .

Parameters Groups, number of animals in group on day 28
Control, n=15 Adjuvant Arthritis, n=11 Hemantane gel, n=8 Diclofenac gel, n=10
Red blood cells, 1012/L 9.09 (8.23; 9.35) 9.44 (8.77; 9.98) 8.94 (8.20; 9.39) 8.70 (8.60; 8.80)
Hemoglobin, g/L 137.00 (133.00; 141.50) 138.00 (134.00; 143.50) 136.50 (126.80; 141.80) 133.00 (127.50; 138.50)
Hematocrit, % 45.53 (40.89; 47.45) 47.38 (46.29; 49.63) 45.17 (40.30; 47.40) 43.78 (43.05; 44.62)#
Platelets, 109/L 434.00 (399.00; 451.00) 412.00 (387.50; 441.20) 438.50 (382.50; 474.20) 495.00 (440.20; 548.80)
Plateletcrit, % 0.23 (0.20; 0.24) 0.21 (0.20; 0.22) 0.21 (0.19; 0.24) 0.26 (0.23; 0.28)
White blood cells, 109/L 16.91 (14.28; 18.96) 17.27 (16.47; 20.29) 13.95 (12.99; 15.9) 16.75 (15.73; 18.67)
Granulocytes, 109/L 4.34 (3.85; 5.20) 4.14 (3.71; 5.55) 4.76 (3.80; 5.37) 4.53 (3.96; 6.93)
Stab neutrophils (%) 1.0 (0.0; 1.0) 0.0 (0.0; 1.0) 0.5 (0.0; 1.8) 0.5 (0.0; 1.3)
Segmented neutrophils (%) 19.0 (16.5; 26.0)@ 20.5 (17.3; 23.3)@ 25.0 (21.3; 27.3)#*@ 26.5 (19.8; 36.0)#*
Eosinophils (%) 0.0 (0.0; 1.0) 0.5 (0.0; 1.5) 0.5 (0.0; 1.0) 0.0 (0.0; 0.5)
Basophils (%) 0.0 (0.0; 0.0) 0.0 (0.0; 0.0) 0.0 (0.0; 0.0) 0.0 (0.0; 0.0)
Monocytes (%) 4.0 (3.0; 4.5) 4.0 (2.8; 6.0) 2.0 (2.0; 3.5) 4.0 (3.8; 5.0)
Lymphocytes (%) 74.0 (71.0; 77.5) 73.5 (69.8; 78.0)@ 71.0 (69.5; 74.8)@ 69.5 (58.0; 76.3)

* P < 0.05 vs. control group, Mann–Whitney U test; # P < 0.05 vs. adjuvant arthritis group, Mann–Whitney U test; @ P < 0.05 vs. day 14 after the injection of FCA, Mann–Whitney U test; data are expressed as median (Q1; Q3).