Table 3.

Proteins and their Kcr sites associated with crotonylation.

Protein Names	Enter Name	ID	Sites	Diseases and Biological Processes	References
Histone 2b	H2b	–	K12	Hypertrophic cardiomyopathy (HCM)	[30]
Histone 2b	H2b	–	K86	Metabolic homeostasis, Hepatocellular carcinoma	[54,100]
Histone H3	H3	Q6NXT2	K18	Autosomal dominant polycystic kidney disease (ADPKD), HCM	[30,64]
Histone H3	H3	Q6NXT2	K27	Depression, Alzheimer's disease (AD)	[81,85,86]
Histone H3	H3	Q6NXT2	K4	HIV	[89]
Histone H4	H4	P62805	K77, K91	Stem cell endoderm differentiation	[22]
Enolase 1, chloroplastic	ENO1	Q9C9C4	K40	colorectal cancer	[27]
Protein ENL	ENL	Q03111	S46	Wilms tumor	[122]
Cellular tumor antigen P53	P53	P04637		Render the tolerance of cancer cells to chemotherapeutics and drugs	[17]
Platelet glycoprotein 4	CD36	P16671		Chronic renal failure (CRF)	[69]
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	IDH3a	Q9D6R2	K199	Ischemic heart disease (IHD)	[72]
Microtubule-associated protein RP/EB family member 1	EB1	Q8WQ86	K66	Spindle positioning	[94]
Tropomyosin alpha-1 chain	TPM1	P58771	K28	Ishemia-Reperfusion Injury	[72]
Brain expressed X-linked gene 2	BEX2	Q9BXY8	K59	Non-small lung cancer	[51]
Septin2	SEPT2	Q15019	K74	Hepatocellular carcinoma (HCC)	[52]
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	MTHFD1	P11583	K354, K553	Pancreatic cancer	[53]